Description and Brand Names
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Anastrozole is used to treat early hormone receptor-positive breast cancer. It is also used for first-line treatment of hormone receptor-positive or hormone receptor-unknown advanced or metastatic (cancer that has spread) breast cancer. Anastrozole is also used to treat advanced breast cancer that has grown or spread after tamoxifen treatment. This medicine is used only in women who have already stopped menstruating (postmenopausal).
Many breast cancer tumors grow in response to estrogen. This medicine interferes with the production of estrogen in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor.
This medicine is available only with your doctor''s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
Heartburn Remedies Natural Remedies (🔴 Remedies) | Heartburn Remedies Acidityhow to Heartburn Remedies for The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For breast cancer:
- Adults—1 milligram (mg) once a day.
- Children—Use and dose must be determined by your doctor.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
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Keep out of the reach of children.
Do not keep outdated the 1 last update 31 May 2020 medicine or medicine no longer needed.Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
It is very important that your doctor check your progress at regular visits to make sure that this for 1 last update 31 May 2020 medicine is working properly. Blood tests may be needed to check for unwanted effects. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.
It is unlikely that a postmenopausal woman may become pregnant. But, you should know that using this medicine while you are pregnant could harm your unborn baby. Use an effective form of birth control during treatment with this medicine and for at least 3 weeks after the last dose. If you think you have become pregnant while using this medicine, tell your doctor right away.
Do not use this medicine together with tamoxifen (Nolvadex®, Soltamox®).
This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have itching, hives, hoarseness, trouble breathing or swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
Check with your doctor right away if you start having chest pains or difficulty with breathing. This medicine may increase the chance of heart problems, including heart attack, in women for 1 last update 31 May 2020 who have a history of ischemic heart disease. Check with your doctor right away if you start having chest pains or difficulty with breathing. This medicine may increase the chance of heart problems, including heart attack, in women who have a history of ischemic heart disease.
This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, talk to your doctor.
This medicine may increase your cholesterol or fat in the blood. If this happens, your doctor may give you medicine to lower the cholesterol and fat.
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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- Blurred vision
- bone pain
- chest pain or discomfort
- pounding in the ears
- slow or fast heartbeat
- swelling of the feet or lower legs
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- Arm, back, or jaw pain
- chest tightness or heaviness
- cough producing mucus
- difficult or painful urination
- difficulty breathing
- dizziness, severe
- headache, continuing
- increased blood pressure
- lower back or side pain
- pain, tenderness, bluish color, or swelling of the foot or leg
- sore throat
- unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
- vaginal bleeding (unexpected and heavy)
Incidence not known
- Blistering, peeling, or loosening of the skin
- dark urine
- difficulty swallowing
- dry mouth
- general tiredness and weakness
- hives or welts, itching, skin rash
- incoherent speech
- increased urination
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- light-colored stools
- loss of appetite
- metallic taste
- muscle weakness
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red skin lesions, often with a purple center
- red, irritated eyes
- sores, ulcers, or white spots in the mouth or on the lips
- stomach pain
- upper right abdominal pain
- weight loss
- yellow eyes and skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Back pain
- body aches or pain
- decrease in height
- feeling of warmth
- flushing or redness of the skin, especially on the face and neck
- increased appetite
- lack or loss of strength
- mood or mental changes
- pain in the back, ribs, arms, or legs
- pain, general
- pelvic pain
- runny nose
- stomach discomfort or upset
- tender, swollen glands in the neck
- trouble in swallowing
- voice changes
- breast pain
- dryness of the vagina
- general feeling of discomfort or illness
- joint stiffness
- loss of hair
- numbness or tingling of the hands or feet
- trouble sleeping
- weight gain
Incidence not known
- Difficulty in moving
- muscle cramps or stiffness
- swollen joints
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: Feb. 01, 2020
Original article: https://www.mayoclinic.org/drugs-supplements/anastrozole-oral-route/side-effects/drg-20061868
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